Table of Contents

Basic Overview
- Special Modifiers
- Scoring and Ranking
Strategy

Neural Simulation (“Neural Sim” or “NS” for short) is a game mode where you fight one of two bosses that change weekly. Your goal is to defeat both bosses as fast as possible.

Basic Overview

The Neural Simulation menu can be found in the Dispatch section of the main mission menu.

Once in the menu, you’ll see the following UI elements:

The two bosses on rotation in the current Neural Sim period, click on the boss you want to fight to switch to them
Time left in the current Neural Sim period. Neural Sim periods always end at the same time on the daily reset of each new in-game week. After a Neural Sim period ends, this timer will instead count down the time until the next Neural Sim period opens. Neural Sim periods always begin at 2:00AM UTC on Tuesday (convert to your time zone)
Boss description. The bottom of the boss description will list which Control effects it’s vulnerable to (though you can also find a full table of which bosses are vulnerable to which Control effects further down on this page).
The current difficulty level of the selected boss. Difficulty levels start at one and reach a maximum of five, and are independent of the difficulty level of the other boss. Once you go up a difficulty level for a boss, you can not go down difficulty levels for that boss in the current period (not that there’s any reason to).
Evaluation attempts remaining. Clearing the first four difficulty levels of a boss requires an evaluation attempt to be consumed. You will have a limited number of evaluation attempts for the first day of the Neural Sim period only; you will have enough to clear the first four difficulty levels for both bosses from the second day onward. Attempting difficulty level five for a boss does not require evaluation attempts.
The lineup of characters and equipment that has produced the highest-scoring run for that boss.

Clicking on the lineup will bring up a menu with more details. Keep in mind what you have used on a certain boss is very important, as everything used (operatives, weapons, and logistics pieces) can no longer be used on the other boss during the same Neural Sim period unless another run with a different lineup is confirmed for the first boss.

This run does not have to score higher than the existing one.

If you have not fought the boss yet, the lineup will be blank, obviously.

Buttons to proceed towards fighting the boss or performing a Quick Evaluation. Quick Evaluation will automatically clear a boss that is at one of the first four difficulty levels and grant you the associated score. Quick Evaluation cannot be used on Difficulty V bosses.
The Neural Sim rewards menu. Here you can view and collect rewards for completing Neural Sim clears, as well as view your placement on the ranking leaderboard along with the rewards for each ranking bracket.

The Neural Sim shop, where you can use the rewards obtained to purchase various items. You can also access this shop via the main shop interface from the home menu.

Special Modifiers

*Weekly modifiers are listed as a Protocol, while individual boss modifiers are listed as Attribute Buffs. Make sure to scroll the list so you can see all the modifiers.*

Neural Sim battles have unique modifiers that will affect the stats of your operatives. These effects change every week, and include both individual modifiers for each boss, as well as a single modifier for the week that affects both boss battles. Before you fight a Neural Sim boss, it’s important to know what modifiers are in effect for that battle and plan accordingly if necessary.

As well, bosses will gain upgrades to their abilities to make them more difficult or time-consuming to battle. These upgrades are unique to each boss but stay the same between appearances.

As you go up in difficulty level, more modifiers will take effect, and the boss will gain access to more upgrades.

Scoring and Ranking

For the first four difficulty levels of a boss, the score obtained from clearing that difficulty level is a set amount regardless of the time taken to clear. However, Difficulty V works differently. The maximum score possible is 40,000 but with your score decreasing by 100 for every second taken to defeat the boss. For example, killing a boss in exactly 60 seconds will subtract 60×100=6,000 points from 40,000 to produce a score of 34,000. Therefore, achieving victory as quickly as possible is important to obtaining high scores and ranking placements.

Strategy

Neural Sim is a score-based game mode, with higher scores correlating to faster fights. Thus, Neural Sim requires a slightly different mindset compared to general content, which is typically much easier. Since you will be exclusively fighting bosses, there are also other things that should be taken into account.

Control Effects

Bosses in Snowbreak have a period of time (roughly 14 seconds) where they cannot be affected by a Control effect after one is applied.

This lockout period is visually represented by a golden yellow bar underneath the main boss health bar, which depletes over time until disappearing to signify that the lockout period is over. The lockout also does not begin counting down until the Control effect expires.

Furthermore, not all Control effects work on all bosses. Most bosses are only vulnerable to two types of Control effects at most:

Control Effect	Generally Affected Groups	Specific Bosses Affected
Stun	Humans	Esther, Sartre, Will (both variants), Katya (both variants), Gavin, Joseph (both variants)
Freeze	Titans	Beauvoir 13, Hela (both variants), Fiend - Foehn, Njall (both variants), Lament of Yehrus, Nightborne Phantom, Snowbreak Aku-MA
Paralyze	Mechanical Enemies	Ni-Type Mech (both variants), Cerberus, Teumessian, Joseph - Hardened, pi - Purified
Slow	All	All except Snowbreak Aku-MA

Note that every Neural Sim boss can be affected by Slow with the singular exception of Snowbreak Aku-MA, which makes operatives who can effectively apply it universally useful.

Team Building

In the current meta, teams consist of one main DPS operative and two supports. This is because it is much more efficient to focus on buffing up a single DPS than it is to spread power between multiple.

DPS

When selecting a DPS operative, it is important to take into account what supports you can pair with them, the boss that is being fought, and any relevant weekly modifiers. For example, you probably shouldn’t bring Yao - Winter Solstice to a boss with Thermal resistance on the weekly modifiers list.

While you can make do with most DPS operatives, there are a few worth mentioning as the top performers:

Supports

Once you select your DPS, you will ideally pick two supports to bring out their potential and allow your DPS to do as much damage as quickly as possible. Keep operative synergies in mind too!

There are a lot of options available to you, perhaps more than you initially thought. Here’s a quick rundown of the common ones you might consider, though this isn’t an exhaustive list:

A Quick Note on Healers And Other Defensive Supports

Neural Sim does not reward you for clearing with extra health. In fact, there is a weekly modifier that may show up which reduces your damage while over half health, so you may find that not taking damage is actually a demerit in some cases. Either way, there’s no reason to worry about taking damage as long as the attack doesn’t stagger or knock back the active operative (time loss) and none of your operatives die.

This means that healers and other defensive supports should only be used if absolutely necessary, and more offensive supports that directly buff your active operative or debuff the enemy are always preferred when possible.

Parts Breakers

For some bosses, it will be necessary to break parts on them to progress the fight. In general, shotgun operatives will be ideal for this due to their innate high parts break rate. There are a few other options, though, each with their own benefits:

When looking to deploy an operative for parts breaking purposes, also remember to equip any weapon attachments that provide parts breaking boosts. It can mean the difference between breaking a part or needing an extra shot.

Logistics Sets

For DPS operatives, they will usually just use the set that they normally use, but supports have a bit more diversity in their options:

Logistics Set	Role	Additional Notes
Xinye	U-Energy Generation	Niche usage
Twilight	Debuffing	Requires the equipped operative to be of the same element as the DPS to be effective
Navigator	Debuffing	Only useful on supports capable of applying Control
Amarna	Buffing	Requires continuous damage from support skill for maximum effectiveness
Phantom	U-Energy Generation	Niche usage

Support Weapons

Support weapons generally fall under three categories: attack boosters, resistance shred debuffers, and U-Energy generation boosters. Attack buffers are generally the preferred choice, but the other options may still be useful if that is not an option.

Weapon Effect	Weapons	Additional Notes
Attack boost	Wave, Frigatebird, Deep Sea’s Call, Lapis Lazuli, Prismatic Igniter, Strawberry Shortcake, Trial’s Eve, Alloy Truth	Wave is event-exclusive and scales off of the equipped operative’s HP rather than ATK unlike most the others in this group. Trial’s Eve also scales off the active operative’s ATK, rather than the equipping operative’s ATK. Alloy Truth gets a special mention as arguably the best support weapon in the game, providing a large ATK buff scaling with max HP, as well as a crit damage boost.
Resistance shred	The Past’s Sigh (SMG, Kinetic), Disco Confusion (Chaos, Sniper), Valkyrie 2056 (Thermal, Shotgun), Aye Aye Captain (Frost, Pistol), Duckling (Electric, AR)	Each weapon will reduce the resistance for a different element, which may make it difficult to bring the right one. Damage also has to be dealt by the equipped operative’s support skill to activate the weapon effect.
U-Energy Generation	Eccentric Joker, Wasp, Odd Alley Cat	Eccentric Joker and Wasp have limited usefulness when not equipped to Tess.

Know Your Enemy

Being familiar with a boss’ attack patterns, phase changes and their HP thresholds, and other quirks they might have is important to being able to defeat them as quickly as possible. Don’t be afraid to rerun a boss to figure out what attacks you have to dodge and which ones you can sidestep or facetank, or to see how long you can spend attacking before you have to dodge an attack.

Yao - Winter Solstice	Yao is one of if not the best operative for many of the bosses you’ll see in Neural Sim, and at least usable in all the others. To extract top performance out of her though, you’ll want to put her with Mauxir - Shadow Ka and Tess - The Magician whenever possible.
Chenxing - Ethereal Cloud	A very strong all-rounder, Chenxing especially excels against bosses with multiple parts that she can lock onto with her standard skill. This makes her particularly effective against Cerberus, Fiend, and her main claim to fame, Hela, who gets ripped to shreds.
Fenny - Coronet	While still a very strong DPS pick, Coronet finds herself sometimes being overshadowed by other operatives and can struggle to keep her gun loaded with ammo given its sequential loading.
Katya - Blue Bolt	Very similar to Chenxing in that she’s a strong generalist DPS. Katya benefits from never having to reload but also can have issues tracking more mobile bosses given that her crossbow projectiles are not hitscan.
Fritia - Hush	A high-investment operative that eventually pays off with some of the fastest Neural Sim clears in the game. Requires Tess to be effective.
Lyfe - Wild Hunt	Hybrid gun/skill damage operative. Like Hush, she also requires heavy investment.
Marian - Swift	Another high-investment operative, Swift can be especially strong against mobile bosses due to her ability to lock onto her target.
Haru - Absconditus	While not useful for most bosses in the game, Haru earns a special mention given her effectiveness against Fiend when equipped with Star Ocean.
Cherno - Enigma	Provides very strong, sustainable burst damage delivered via skills and not shooting.
Siris - Ksana	Strong, sustainable burst damage that scales up over time.
Lyfe - Infinite Sight	Strong Kinetic DPS that's highly mobile and capable of locking onto enemies.
Vidya - Agave	Limited viability as a DPS outside of her designated pandering boss, Nightborne Phantom.

Operative	Primary Role	Additional Notes
Tess - The Magician	U-Energy Battery	The vast majority of Tess’ usefulness is in her ability to generate large amounts of U-Energy. It is generally not recommended to use her if this niche is not required, as other supports will most likely provide more value.
Mauxir - Shadow Ka	Offensive Utility	While Mauxir doesn’t directly buff the DPS outside of her passive, she provides a stationary target linked to the targeted enemy’s health which can also come with guaranteed crits to shots made at it.
Lyfe - Wild Hunt	Buffer	When equipped with Alloy Truth and Amarna Squad, Lyfe can become a very strong damage buffer due to her support skill being able to activate both parts of Amarna’s effect. She can also apply Freeze to most Titan bosses.
Acacia - Kaguya	Debuffer/Buffer	Provides universal resistance shred, which will always be useful. Kaguya can also make use of Amarna Squad exceptionally well, allowing her to pull double-duty as a buffer too.
Chenxing - The Observer	Buffer/Healer	While Chenxing’s support skill provides a heal, her primary usefulness comes from the skill damage buffs that come with it.
Acacia - Redacted	Debuffer	The best Slow applier in the game. Acacia also provides starting U-Energy, which can be useful to certain DPS operatives.
Lyfe - Wednesday	Debuffer	Can apply Paralyze.
Fritia - Little Sunshine	Buffer	The aptitude effect from her support skill is especially potent with shotgun operatives. Her Deiwos passive that increases damage dealt to burning enemies has great synergy with Yao - Winter Solstice.
Enya - Big Sis	Buffer	While her time in the spotlight has long since passed, Enya can still find niche use with sniper operatives if all other options are already exhausted.
Cherno - Those Two	Debuffer	The other main Slow applier. Not as universally usable as Redacted, but she can equip Alloy Truth and is good enough against melee bosses to be worth considering.
Yao - Quiet Quitter	Healer	See “A Quick Note on Healers And Other Defensive Supports”
Siris - The Goldfish	Defensive Utility	See “A Quick Note on Healers And Other Defensive Supports”
Eatchel - The Cub	Healer/Buffer	Can provide very strong attack buffs in extended fights. Otherwise, see “A Quick Note on Healers And Other Defensive Supports”
Enya - Exuvia	Sub-DPS/Buffer	Provides strong skill damage buffs, but also has extra synergy with certain DPS operatives. Her support skill can also provide interruption resistance.
Fenny - Starshine	Ballistic Damage Support	Provides extra ammo and ballistic damage buffs, giving her strong synergy with ballistic damage DPS units.
Vidya - Agave	Debuffer/Buffer	Can apply Paralyze, and provides a small attack boost on top. Not worth using as a pure attack buffer.